Scarce early monograph on human subject research by the pioneering medical ethicist, whose work was foundational to the current understanding of informed consent.
"The central conclusion is that it is unethical and immoral to carry out potentially dangerous experiments without the subject's knowlege and permission."
Comprehensive and lucid overview of the history, methods, purposes, justifications, ethical exigencies, and rules surrounding the practice of human subject research in medicine, with a discussion of the 1947 Nuremberg Code on human experimentation. Beecher, a Harvard anaesthesiologist, is remembered for his extraordinarily influential 1966 paper on unethical human experiments, and this work – his "ﬁrst major foray into the ethics of human experimentation" (Capron) – typifies his early thinking on the issue. A contemporary reviewer in the Archives of Internal Medicine, who recalled hearing "no self-conscious, or even casual, discussion of the ethics of experimentation until after World War II," concluded that "this book should be in the hands of anyone who has to make any decisions about clinical experimention."
First published in the Journal of the American Medical Association, and reprinted here as Publication Number 352 in the American Lecture Series / A Monograph in American Lectures in Medicine.
Read more: Capron, "Henry Knowles Beecher, Jay Katz, and the Transformation of Research with Human Beings."
Springfield, IL: Charles C. Thomas, . 8.5'' x 5.5''. Original gilt-stamped black pebbled wrappers. 80 pages. Pen to front endpaper and a very few instances of restrained pencil underlining, else fine.
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